Sentence examples for binding model involving the from inspiring English sources
Further experiments showed that a 2 1 binding model involving the external binding of TO-CZ to both ends of the G-quadruplex is the most possible binding mode.
Class B G protein-coupled receptors are activated by their cognate ligands following a two-step binding model involving a specific network of ligand-receptor intermolecular interactions.
The results were interpreted in terms of a surface binding site model involving two modes of product inhibition.
As the active site residues that constitute the chemically distinct binding pockets do not share the same p Ka values, the almost superimposing pH profile curves shown in Figure 3 refute a model involving separate binding sites for the two DCS binding events.
Increasing experimental evidence supports the ATP-binding induced sliding clamp model involving a mobile MutS MutL complex [ 41, 42], at least for the communication of mismatch recognition and strand discrimination.
Moreover, a cyclic degradation model involving sequential binding of NRF2 first to the ETGE motif and then through the DLG motif has been proposed [ 13].
The data provide further support for the model involving direct competition between ToMOC and ToMOD for binding to the hydroxylase.
The predictive models offer new insights into binding modes involving the hydrophobicity and flexibility of the active site.
The reduced affinity of exon10 binding to full-length protein compared to SH3 domain is consistent with a competition of free exon10 with the endogenous exon10 SH3 complex and thus supports an autoinhibition model involving exon10 SH3 binding.
At least with respect to the binding sites involving the G domain, H-Ras is an excellent model for K-Ras and probably N-Ras as well.
In addition, a significant correlation was observed of measured binding affinities with binding affinity values predicted using a thermodynamic model involving DNA and RNA unfolding, ODN hybridization, and RNA restructuring to a final free energy minimum.
