Sentence examples for binding mode of an from inspiring English sources

As such, it helps to get a better understanding of the binding mode of an inhibitor.

Understanding the binding mode of an antagonist in the SMO receptor is crucial for the rational design of new antitumour agents.

To our knowledge, these are the first structures of MK2 showing the binding mode of an inhibitor with high binding affinity (IC50 8.5 nM).

Thus, the heat map coloring should be considered as complementary to structure based approaches and as such help to get a better understanding of the binding mode of an inhibitor.

From this test, there was only one fully solved binding mode of an HLA-drug complex available (abacavir) and two other proposed HLA-B*57 01 HLA-B*57 01ounds (flucloxactiven and pazopanib) from the use of odds ratios.

We report that by manipulating the binding mode of an antibody fragment to the transferrin receptor (TfR), we have developed a Brain Shuttle module, which can be engineered into a standard therapeutic antibody for successful BBB transcytosis.

Predicted binding mode of a new curcumin derivative in complex with 12-LOX active site.

Fig. 3 Predicted binding mode of A new curcumin derivative in complex with 12-LOX active site.

Raha and Merz used semi-empirical QM based scoring function for predicting binding energy and binding mode of a diverse set of protein-ligand complexes [22].

We describe multi-conformation simulated annealing-pseudo-crystallographic refinement (MCSA-PCR), a technique developed for predicting the binding mode of a flexible ligand in a flexible binding pocket.

We determine the binding mode of a macrocyclic radicicol-like oxime to yeast HSP90 by combining computer simulations and experimental measurements.