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Despite these results, the approximate binding affinity calculation will still be useful to assess the docking of complexes when the binding mode is unknown.
As the optimal parameter set depends on the characteristics of the samples and there is no consistent threshold across different conditions for peak calling, then investigation of a protein whose binding mode is unknown necessitates the setting of threshold parameters for peak calling by trial and error.
Similar(58)
This means that the RNA binding mode is preserved.
The first binding mode is adopted by the H3 peptides, whereas the other mode is adopted by the H4 peptides.
However, their binding mode is entirely different.
The previously unknown binding mode was used as a basis for the design of a new ligand with similar affinity to others binding this pocket.
The predicted binding mode was confirmed by X-ray crystallography.
The binding mode was proposed from a docking study.
Similar binding mode was observed in MdOS and EGFR kinase.
The binding mode was modelled by molecular docking.
An alternative His/Met binding mode was also investigated.
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