Sentence examples for binding mode is highly from inspiring English sources

The observed SWI/SNF nucleosome binding mode is highly distinct from the prevailing model in which nucleosomes are either bound in a cleft of SWI/SNF (Dechassa et al., 2008) or are caged by RSC (Chaban et al., 2008).

Considering that in the actual substrate, the D-amino acid would be linked to the tRNA, a multiple binding mode is highly improbable as the orientation and position of the D-amino acid would be fixed by the binding of terminal adenosine.

This means that the RNA binding mode is preserved.

The first binding mode is adopted by the H3 peptides, whereas the other mode is adopted by the H4 peptides.

However, their binding mode is entirely different.

This binding mode is consistent with the observed experimental SAR (vide infra) and is significantly different from the two closely related binding modes previously postulated in the literature.

By contrast, binding mode 4 was clearly disfavored in chain A, indicating that this binding mode is incompatible with the partially constrained (active) conformation.

Among these inhibitors, compound 20x showed highly selective and potent GSK-3β inhibitory activity in vitro and its binding mode was determined by obtaining the X-ray co-crystal structure of 20x and GSK-3β.

The predicted binding mode was confirmed by X-ray crystallography.

The binding mode was proposed from a docking study.

Similar binding mode was observed in MdOS and EGFR kinase.