Sentence examples for binding mode indicating that from inspiring English sources

There are very significant differences in the binding mode indicating that the binding location in B*57 01 most likely occurs in a different region of the pocket than where the docking grid was generated using abacavir.

Moreover, docking studies on 10i with ntMGAM presented a new binding mode, indicating that amino residue Asp542 should be the key interacting point for strong inhibitory activity of small molecules against α-glucosidase enzymes.

These significant variations in flucloxacillin's binding modes indicate that molecular dynamic studies will be needed in order to further investigate the potential binding mode(s) between B*57 01 and flucloxacillin.

The predicted binding modes indicate that the substituted aromatic rings closely mimic Val3 and Leu7 in annexin A2, interacting with the hydrophobic pockets of S100A10.

SSB- dT 70 complexeSSB- dT 70reversible forcomplexesd transitions bexhibitmodes without dissociation and SSB can diffuse along ssDNA in the differeversibleng modes, indicating a highly dynamic complex.

In all the cases, the low energy binding modes indicate thermodynamically favourable interaction.

The mixed inhibition mode indicates that these inhibitors are able to bind to the substrate enzyme complex as well as to the free enzyme, whilst the competitive mode indicates binding only to the free enzyme.

The binding mode analysis indicated that all of these inhibitors are well accommodated in the active site and interact with the key amino acid residues of Catalytic anionic site (CAS) and peripheral anionic site (PAS).

In addition, computational predictions of the fitting of saponins to the topoisomerase I DNA complex, indicate a similar binding mode to that of clinically used topoisomerase I inhibitors.

These findings indicate an additional irreversible binding mode of palonosetron that is distinct from the slowly dissociating binding, and may reflect multiple sites of interaction of palonosetron with 5-HT3 receptors.

2) The authors stated that the binding of Doc helix 1 to Coh corresponds to the binding mode A, while that of Doc helix 3 to Coh corresponds to the binding mode B. It will be helpful to indicate all interaction bonds at the binding interface in Figure 1B or in a new figure panel for each binding mode.