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We thus report a systemic and genotype-dependent dysregulation of TDP-43 binding microRNAs in human biomaterial that might reflect an easily accessible biological measure of TDP-43 dysfunction.
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Here, we discuss microRNAs in neurodegeneration, from the fruit fly and mouse utilized as experimental models to dysregulated microRNAs in human neurodegenerative disorders.
The current study provides a novel link between overexpression of collinear Hox genes and multiple microRNAs in human breast malignancy.
To identify microRNAs that are enriched in the human heart, we compared the expression of microRNAs in human fetal heart and fetal liver using microRNA microarrays.
Supplementary Table S2 T. gondii microRNAs expressed in human and rodents.
In particular, for each microRNA considered, a list of 'conserved target' mRNAs was defined by selecting mRNAs with a specific microRNA binding site conserved in humans, mice, rats and dogs.
Cluster analysis of microRNA expression profiles revealed cancer-specific alterations of microRNA expression in human male breast cancer.
Considering these similarities, studies examining microRNA expression during porcine brain development could potentially be used to predict the expression profile and role of microRNAs in the human brain.
Additionally, the performance of the developed method for microRNA assay in human samples is excellent, confirming its practical utility.
To investigate the expression profiles of microRNA (miRNA) in human testes showing different histopathological patterns.
The feasibility of microRNA analysis in human lung cancer cells was also demonstrated.
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