Sentence examples for binding mechanisms of these from inspiring English sources

In order to investigate the binding mechanisms of these inhibitors, in silico docking studies were applied.

While the molecular docking was carried out to predict the most probable inhibition and binding mechanisms of these antibacterial and antifungal agents using the MOE docking suite against few reported target proteins.

To further explore the binding mechanisms of these new inhibitors, we determined the X-ray structures of the complexes of FABP4-9 and FABP4-10, which revealed similar binding conformations of the two compounds.

Thus, the binding mechanisms of these two inhibitors were studied by multiple approaches consisting of enzyme-kinetic analysis, molecular docking and molecular dynamics (MD) simulation 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41.

In the absence of x-ray crystal structure of this enzyme, homology modeling proved to be a reasonable alternate to study substrate binding mechanisms of this enzyme.

Determination of the conformations adopted in vitro and in vivo is crucial in elucidating the binding mechanism of these two compounds.

Moreover, the Pauli principle plays a crucial role in the binding mechanism of the fermions.

Furthermore, the binding mechanism of the non-canonical motifs is poorly understood.

The results suggest that cLac effectively mimics the membrane binding mechanism of the parent protein lactadherin.

In addition, to add new insights into the binding mechanism of the inhibitor, we designed constrained analogues of ambenonium by incorporating the diamine functions into cyclic moieties (4 12).

They explained the binding mechanism of the enzyme to the gold nanoparticle by covalent interactions between thiol groups in cysteine residues as well as amine groups in lysine residues of pepsin with the surface of gold.