Sentence examples for binding mechanisms in which from inspiring English sources

Intrinsically disordered proteins can follow different binding mechanisms in which preformed elements of secondary structure, together with concomitant folding and flexibility in the unbound and bound state can play important roles [34].

Importantly, the relationship between lignin and enzymatic binding (Fig. 7a) indicates a competitive binding mechanism, in which both enzyme and inhibitor (lignin) bind favorably to the substrate (cellulose).

The potentials that result from interactions involving multiple domains generate a novel, modular binding mechanism in which opposed cadherin ectodomains can adhere in any of three antiparallel alignments.

This supports an ordered substrate binding mechanism in which the catalytic cycle of CaMKII involves the formation of the enzyme-ATP binary complex followed by the enzyme-ATP-protein substrate ternary complex [14], [15].

A two-step binding mechanism in which a faster transient developed at the higher concentrations of 2-OG assayed was identified.

These results suggest a conserved lipid binding mechanism in which Ca2+-independent interactions are mediated via a lysine rich region of the C2B domain while Ca2+-dependent interactions are mediated via the Ca2+-binding loops.

The hyperbolic dependence of the rate constants on the substrate concentration is expected for a two-step reversible binding mechanism in which the first step is electroneutral and the second electrogenic.

The authors reported that 26% of the genes encoded secreted proteins and of the 106 unigenes identified 15 were involved in trafficking and mineral binding, mechanisms which they suggested probably contribute to construction of the shell.

The latter observation might suggest that the mechanisms in which FKBP5 is involved in treatment response are downstream of the primary binding profile of antidepressant drugs.

These observations thus argue against a cooperative binding mechanism in the tandem UIMs binding with Ub.

It has previously been shown that SOS can be prevented from binding to Ras by an autoinhibitory mechanism, in which the Ras binding site on the catalytic domain of SOS is blocked by another portion of the SOS protein.