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It is solidly established that the enzyme cleaves proteins and peptides on the carboxyl side of lysine and arginine residues employing a well-understood specific binding mechanism that recognizes the basic side chains of those amino acids.
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Besides, the macrophages also execute an innate host surveillance mechanism that recognizes intracellular bacteria [27].
How could secular societies find a binding mechanism that effectively replaced traditional forms of unity?
The Src homology 2 (SH2) domain is the most prevalent protein binding module that recognizes phosphotyrosine.
Among these receptors is VLDLR, which has a binding domain that recognizes VLDL and vitellogenin.
Tus is a sequence specific DNA-binding protein that recognizes 21 bp Ter sites [24].
It is very important to design a DNA-binding domain that recognizes a specific DNA sequence.
Facile quantitative methods are necessary to study the activities and mechanisms of regulatory sequences and the RNA binding factors that recognize them.
FBP1, FBP2, and FBP3 are single-strand DNA-binding proteins that recognize FUSE.
Because the CU-rich sequence overlaps with the predicted binding site of U2AF65, a factor that recognizes the polypyrimidine stretch at the 3' end of introns, one possible mechanism of PTB function is a simple competition for the binding site [22].
Subsequent work has revealed that the relatively small effect on Akt activation of ablating binding of PDK1 to PtdIns 3,4,5) P3 is probably due to a second mechanism that brings Akt and PDK1 together and that is mediated by PDK1 possessing a docking site that recognizes Akt after it is phosphorylated at Ser by mTORC2 (mTOR complex 2) [ 67].
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