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Therefore, a defect in Prp3 binding may underlie the splicing defects of these U6 snRNA mutations in yeast and human.
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Differences in SDS binding may underlie both the slow (negative PO4 group) and fast (positive RR residues) migration of these Bak variants on SDS-PAGE.
Spastin also displays an adjacent microtubule binding sequence, and the presence of both ESCRT-III and microtubule binding elements may underlie the recent findings that the ESCRT-III disassembly function of Vps4 and the microtubule-severing function of spastin, as well as potentially katanin and fidgetin, are highly coordinated.
The results suggested that changes in the number and/or nature of cyclin-binding proteins may underlie the evolutionary role of the alterations in the molecular structure of cyclins and their involvement in diverse molecular-genetic events.
Objective To explore whether abnormalities in growth hormone binding protein (GHBP) may underlie the growth restriction associated with fetal aneuploidy.
Thus, decreased LRRK2-mediated Wnt signaling caused by reduced binding to LRP6 may underlie the neurodegeneration observed in PD.
In addition, mice deficient in the APOE-binding LDL receptor (Ldlr−/−) develop ATH [ 67], further accentuated by humanized APOB [ 68], suggesting that differential APOE binding to LDLR may underlie the role of APOE polymorphisms in ATH development.
The different length and composition of the intervening sequences of the RING loops may underlie the binding specificity towards the different E2 enzymes.
The direction, time course, and location of the kindling-induced increase in 3H-CPP binding suggest that this novel receptor may underlie the increased sensitivity of CA3 neurons to NMDA observed in kindled animals.
The detailed analysis of binding cavities within individual AR subtypes indicated small but significant structural variations that may underlie the observed differences in binding affinities of purinediones at particular subtypes and species.
These connections may underlie the cognitive links for semantic binding between action words and referential aspects of their meaning.
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CEO of Professional Science Editing for Scientists @ prosciediting.com