Thus, a number of composite CTCF/TR binding sites may represent a subset of other modular CTCF composite sites, such as groups of multiple CTCF sites or of CTCF/Oct4, CTCF/Kaiso or CTCF/Yy1 combinations.
The p110αEEE545K/p85α Cdc42-binding interface may rep110αEEE545K/p85α Cdc42-bindingat could interfaceI3Kα E545K signalling without affecting wild-type PI3Kα signalling in non-tumayrepresent
It seems that the structural change of RolR during DNA binding and release may represent a special model for the TetR-type transcriptional regulators.
The counterbalancing of Ku-Sir4 telomerase recruitment and Rif1/Rif2 occlusion of Sir4 binding to Rap1 may represent a system for maintaining telomere-length homeostasis in yeast.
Thus, the non-NF-κB binding site enhancers may represent a class of constitutive enhancers that control housekeeping functions in AC16 cells.
Thus, these binding locations may represent an evolutionarily conserved structural feature of several viral polymerases that could be exploited for the development of small molecule therapeutics.
Therefore, the identification of small molecule ubiquitin binding compounds may represent an attractive strategy for anticancer drug discovery.
In this context, the repertoire of Cbl binding proteins in teleosts may represent a case of secondary lineage specific-gene loss after duplication and not an ancestral state.
CIB4, encoding calcium and integrin binding family member 4, may represent a further HGF candidate gene considering that calcium channel blockers can induce gingival hyperplasia.
