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Subsequent Spt4/5 binding may render the initiation elongation transition irreversible, because it sterically enforces the nucleic acid arrangement and prevents RNA release and reassociation of DNA strands.
Similar(59)
This was attributed to the availability of numerous binding sites, the presence of which may render the competitive effect insignificant (Apiratikul and Pavasant 2006).
Under this scenario, the interaction of one subunit with substrate may render the other subunit more capable of binding substrate (or releasing products) through allosteric effects.
Even minor changes in the hemagglutinin molecule may affect receptor binding specificity of the virus, and a single point mutation in the neuraminidase may render the virus resistant to oseltamivir.
One hypothesis is that in vivo binding of methadone to the plasma glycoprotein alpha-1-acid glycoprotein (AGP), to a degree dependent on the molecular structure, may render the drug inactive.
Ultimately, mutual distrust may render the evidence largely irrelevant.
Just consider: machinery "may render the population redundant"!
The order of the complexity may render the solution impractical.
This may render the cells anti-apoptotic and may eventually lead to malignancy.
This may render the dementia treatment ineffective.
This may render the cells vulnerable under challenging/disease conditions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com