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This cell surface localised binding may regulate an AnxA2-dependent EGFR signalling pathway.
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The C-elegans homolog of Kirrel3 (an adhesion molecule named syg-1) is located at synapses [ 38] and hence, amphysisin binding may regulate Kirrel3 A presence at neural synapses or neuromuscular junctions.
ECM binding may regulate VEGF-dependent vascular patterning by controlling VEGF diffusion and gradients through tissues [5], [13] and possibly by mediating solid-state binding to VEGFRs [3], [14] [16].
We show in this paper that ATP binding also inhibits its interaction with Stau2 (Fig. 4) suggesting that hsc70 through ATP binding may regulate the release of mRNAs and/or control the dissociation of Stau2-containing RNPs.
In addition to protein-coding regions, approximately 2-62-6% all binding sites were located in mammalian lncRNAs, indicating that RBP binding may regulate the cellular functions of lncRNAs.
Once on vesicles, additional Rab6A binding to the motor domain binding may regulate the load that other motors on the vesicle experience, by blocking KIF1C engagement with microtubules.
NASP, an H1 histone binding protein, may regulate early events of spermatogenesis [42].
We examined how Ndel1, a cytoplasmic dynein binding protein, may regulate non-vesicular bidirectional transport.
A variety of RNA-binding proteins may regulate miRNA function in a spatiotemporal manner or in response to a specific signal during animal development.
The actin binding proteins may regulate cytoskeletal dynamics in developing larvae.
Cellular retinoic acid binding proteins may regulate the interactions between retinoic acids and their nuclear receptors by regulating the concentration of present retinoic acids [ 5].
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