Sentence examples for binding may induce an from inspiring English sources

As to notch activation, Kopan and Ilagan [ 18] proposed two feasible models including the mechanotransduction model (i.e., the mechanical strain may expose site 2 of a notch receptor for protease cleavage) and the allosteric model (ligand binding may induce an allosteric change into a protease-sensitive conformation).

This type of binding may induce a conformational change in the acyl pocket loop which modulates the catalytic site via a domino effect.

As experiment and simulation indicate that the presence of water can invert the sphalerite wurtzite stability relations in nanosize materials, we investigated the possibility that water binding may induce a structural transition.

Membrane binding may induce a conformational change that facilitates the interaction with Vps25 (ESCRT-II) [25,46].

This homophilic binding may induce RIP and thereby a positive feedback-loop, contributing to loss of proliferation control.

It is well known that substrate binding may induce so-called occluded conformations, which have been captured in a number of reported crystal structures (Deng et al. 2015).

It has been proposed that substrate coproporphyrinogen binding may induce rotation around the C5′ S bond of SAM #2, moving the sulfonium sulfur atom of SAM #2 closer to SAM #1.

However, in chronic EAE sections MBP accumulated also around neuronal cells, such as Purkinje cells, as can be seen in sections Figure 4E and F. Indeed, it was recently shown that MBP binding may induce neuron-specific toxicity by direct damaging the neuronal plasma membrane integrity.

Oxidation of Met44B, which is located close to the first Ca2+ binding pocket (31B-42B), may induce a conformational change in the second Ca2+ binding pocket 63B-74BB), whinvolvesLys73Bys73B, as these two Ca2+ binding pockets are hydrogen-bonded to each other.

Expression of NKG2D ligands may induce an immune response through binding to the NKG2D receptor, present on NK cells and a subset of T cells [ 11].

Dkk2 binding to Lrp6 may induce a conformation where this autoinhibition is blocked, leading to receptor activation.