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Nevertheless, it is located in a similar position to the RNF125 C2HC ZnF (Fig. 8D) and also makes extensive contacts with the first Zinc binding loop of the RING domain (Fig. 8E).
First, both the length and the amino-acid composition and distribution of the CDR-H3 loop of the crossreactive CK138 resembles that of the N-terminal extracellular binding loop of the promiscuous CXCR2 reCXCR2r48.
Conversely the phosphate binding loop of the electron transfer flavoprotein is located in the second βαβ unit.
The new structures provide insight into the functional role of the fosfomycin phosphonate binding loop of the enzyme.
CDC25 family member CDC25B regulates the G2/M phase transition by removing two inhibitory phosphate groups from the ATP binding loop of the CDK2 kinase.
Since FtsK forms a hexamer ring structure, when the first subunit moves along DNA, the DNA backbone is brought closer to the DNA binding loop of the second subunit.
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Here we studied the flexibility of the binding loops of the αβ TCR A6 using crystallographic, spectroscopic, and computational methods.
These results suggest the lipid binding region of C2F is restricted to the putative calcium binding loops of the domain and that the interaction with anionic lipids in the bilayer is calcium-independent.
Finally, shifts in the emission spectra of an environmentally sensitive fluorescent unnatural amino acid indicate that the calcium binding loops of the C2F domain directly interact with the lipid bilayer of negatively charged liposomes in a calcium-independent manner.
According to the preferred rotation we identified, the Ca2+-binding loop of the synaptotagmin C2B domain points straight toward the v-membrane in the C2B/SNARE complex.[9] The Ca2+-binding loop is the structure that inserts into the membrane in response to the Ca2+ signal.
The reported glycogen regulation occurred both in the presence and absence of AMP and was dependent on its binding to the carbohydrate-binding loop of the CBM.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com