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Indeed, an analysis of 89 genes whose promoters (1000 bp upstream of the TSS) possess at least one experimentally determined high-quality Myc binding locus on human P493 B cells [ 29] provided no overlap with promoters of genes in mouse lung adenocarcinoma reported in the present study.
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As a control, we also analyzed the β-actin locus on human chromosome 7 (Figure 3C).
MUC5AC and MUC5B genes are closely located at a locus on human chromosome 11.
Our experiments identified 4323 candidate HIF binding loci and possibly up to 5177 sites, a greater number of loci than might have been expected, as previous studies have identified approximately 400 HIF-1α binding loci in human cells [ 33].
In conclusion, we have identified the major GpVI-binding locus in human collagen type III.
Forensic scientists usually analyze 13 specific locations, or loci, on human chromosomes to obtain a complete DNA profile.
The nucleus image (a) shows live cell CRISPR labelling of specific loci on human chromosomes 1 and 13 and is provided by H. Ma and T. Pederson.
Hein, K. L. et al. Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
Therefore, in vitro binding studies on human NET membranes were performed in a cell harvesting protocol.
Nakamura, T., Kubagawa, H., Ohno, T. & Cooper, M. D. Characterization of an IgM Fc-binding receptor on human T cells.
Fig. 8 NET-binding of [11C]Me@HAPTHI on human NET expressing cell membranes using a harvesting protocol.
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