Sentence examples for binding loci in human from inspiring English sources

Our work here proposes a simple analytical model that is potentially representative of multiple transcription-factor binding loci in human disease.

Our experiments identified 4323 candidate HIF binding loci and possibly up to 5177 sites, a greater number of loci than might have been expected, as previous studies have identified approximately 400 HIF-1α binding loci in human cells [ 33].

In conclusion, we have identified the major GpVI-binding locus in human collagen type III.

Using ChIP-Seq data for FoxA2 binding loci in mouse adult liver and human HepG2 cells we compared FoxA binding-site predictions for four computational models of two fundamental classes: pattern matching based on existing training set of experimentally confirmed TFBSs (oPWM and SiteGA) and de novo motif discovery (ChIPMunk and diChIPMunk).

Of the 59 Ler-binding loci, 46 overlapped with the Pch-binding loci, and all the Ler-binding loci in S-loops also bound Pch.

Brunet, E. et al. Chromosomal translocations induced at specified loci in human stem cells.

The INK4/ARF locus encodes three tumour suppressors (p15INK4b, ARF and p16INK4a) and is among the most frequently inactivated loci in human cancer1,2.

These cancers possessed copy number alterations targeting key loci in human T cell lymphomagenesis.

Liu, S.J. et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.

Liu, S. J. et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.

Rahseed, B.K., Fuller, G.N., Friedman, A.M., Signer, D.D. & Signer, S.H. Loss of heterozygosity for 10q loci in human gliomas.