Exact(2)
High throughput technologies such as ChIP-Chip [1], [2] and ChIP-sequencing [3], [4] have been successfully applied to map binding locations of individual transcription factors (TFs) at a genomic scale in organisms ranging from yeast to human [2], [5], [6], [7].
Chromatin immunoprecipitation(ChIP) followed by microarray (ChIP-chip) [ 3] or sequencing (ChIP-seq) [ 4] has been extensively used to study the in vivo binding locations of individual transcription factors and cofactors in a wide range of species and tissues [ 1, 2, 5- 9].
Similar(58)
Rather, in combination with E57, E58 and E63, residues E90 and E120 appear to be responsible for determining the preferred binding location of each individual drug in the multifaceted multidrug-binding pocket and may be utilized to preclude anionic and neutral compounds via their collective negative electrostatic field.
Therefore, to assign binding locations to individual genes, we utilized the ClosestGene method in order to capture the TSS-proximal and –distal peaks.
Taken together, these results show that binding locations of NdgR were successfully detected in vivo.
Another possibility is that the ideal binding location of flucloxacillin is located in a different region of the binding pocket (as indicated by superimposition).
This indicates that even though the binding location of DB00631 fluctuates with different peptides, the overall binding affinity is conserved.
The soccer groups say only the location of a team, and not the locations of individual players, should be provided.
Locations of individual maxima and distances in between were determined.
Zhang et al. proposed the notion of location-based keys by binding private keys of individual nodes to their IDs as well as locations [20].
The correlations between the predicted binding scores of individual scoring function and the experimentally measured binding affinities range from 0.644 to 0.216.
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