Sentence examples for binding limitations from inspiring English sources

Since the binding of HaloTag to the HaloLink resin is essentially irreversible, it overcomes the equilibrium-based binding limitations associated with affinity tags and enables efficient capture and purification of target protein, even at low expression levels.

In order to understand the origin of binding limitations observed, we first examined TCR/CD3 distribution over the cell population using FITC-anti-CD3 mAbs (Fig. 3).

Its only real binding limitation is a ban on converting old intercontinental ballistic missile silos to deploy missile interceptors.

We suggest that binding limitation originates via competition between mechanical forces due to hydrodynamic shear stress and molecular bond strength.

While the docking simulations correctly predicted binding trends, limitations in the method, including potentially inaccurate scoring functions, the use of rigid proteins, and a lack of solvation could have contributed to its inability to reproduce the large differences observed in the IC50 values.

To our knowledge, this is the only available method that accounts for the combinatorial possibilities due to binding interface limitations.

In this work, we explore simulations of a more realistic sequence-based model of transcription factor DNA binding, which overcomes limitations of the theoretical model.

For the ligand binding determinations, technical limitations were imposed by the large number of membrane preparations that had to be examined.

Assuming adult CLint values, defined as the tissue-specific drug removal capacity (per gram of tissue) in absence of binding and flow limitations, remain constant within children is conceptually similar to allometric CL scaling, as presented in Eq. 1.

Additionally, Denzel et al. based their calculations for target abundance on sites present in transcriptome 3´UTRs, however, they were unable to rule out that unidentified highly abundant and regulated non coding RNAs (including circRNAs) might substantially contribute to the pool of available binding sites, a limitation acknowledged in their paper [ref-5].

(Thus, an agreement not to invoke the statute of limitations is binding, but an agreement not to plead that a certain contract constitutes an illegal restraint of trade is not).