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In our model we assumed an excess of β-catenin binding ligands in both the cytosol-membrane and nuclear compartments.
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A new fluorescent peptide probe for the detection of Zn2+ was synthesized on the basis of zinc binding ligands in zinc enzymes.
Further, structurally plastic regions have been shown to preferentially attract new binding ligands in vitro by repertoire selection of non-biased libraries of peptides and proteins [49], [51].
Dystroglycan is a cell membrane receptor that organizes the basement membrane by binding ligands in the extracellular matrix.
Saturation transfer difference (STD) NMR spectroscopy is widely used to study weakly binding ligands, in particular to determine the orientation in which a protein and ligand interact.
Recently, the complexity of multiple ligand presentation following physical vascular damage has been investigated by combining collagen and von Willebrand Factor binding ligands, in addition to fibrinogen-derived peptides, onto a single carrier.
Herein, we test the stringency of the iron-binding ligands in P4H.
The decrease in serum free fatty acid levels in fat-DN mice suggests some function for myostatin and/or other Acvr2b-binding ligands in mature adipocytes.
The asparagine residue, occurring actually in all sequenced alpha-type PLDs (Fig. 5), is a Ca2+-binding ligand in the C2 domain of phospholipase A2[ 26].
Such a cavity for binding ligands is lacking in HadB.
Upon binding, ligands often induce conformational changes in the protein.
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