Sentence examples for binding ligands for this from inspiring English sources

This study may help a better understanding of the activation mechanisms of β-CAs from pathogenic fungi as well as the design of tighter binding ligands for this enzyme which is a drug target for novel types of anti-dandruff agents.

Inspired by structure-based design and tailored for combinatorial preparation, a series of novel cyclic peptides has been developed to yield binding ligands for the third PDZ domain (PDZ3) of PSD-95.

The library should be of adequate sequence diversity to contain binding ligands for the target, however, diversity can be limited both by biological censorship of phage-displayed amino acid sequences and by methods of amino acid sequence randomization.

In this case, our approach can be utilized to display specific binding ligands for proteins which will not require the modification of the proteins and will enable their internalization.

Identification of binding sites could facilitate design of DNA binding ligands for capture and detection of insulin and IGF-2.

Phage display selection of combinatorial peptide libraries has demonstrated its almost unlimited potential in identifying binding ligands for many targets.

Their strong anti-cancer effect is likely mediated by the presence of two ER binding ligands for 31 and an ER binding ligand combined with a cytotoxic agent for 86.

There is a pressing need for high-affinity protein binding ligands for all proteins in the human and other proteomes.

One of the high-affinity binding ligands for RAGE is HMGB1.

The unambiguous presence of the catalytic triad (serine, tyrosine and lysine) in hMAT2B, residues known to stabilize SDR substrates for hydride transfer, nevertheless merits the search for potential substrates or binding ligands for hMAT2B, which is currently underway.

Ephrin A1 is the highest affinity binding ligand for EphA1 (Coulthard et al, 2001), although it also binds ephrin A3 and A4 with lower affinity.