Sentence examples for binding kon was reduced from inspiring English sources

They found that when UUG replaces AUG in the mRNA, the rate constant for TC binding (kon) was reduced by ∼40%, while the dissociation rate constant (koff) was increased ∼4-fold, to yield an increase in Kd of ∼7-fold.

The apparent second-order rate constant for cyanide binding (kon) was calculated from the slope of the linear plot of kobs versus cyanide concentration.

However, Koff is reduced (by an order of magnitude or more) and by implication, Kon must also be reduced.

As expected, a decrease in the binding rate kon was sufficient to reproduce a slower onset of responses to non-saturating [GABA].

For example when 1 mM ertapenem was added to the cis side of the lipid membrane, the association rate constant (kon) was 9100±1000 (Ms)−1 and the binding constant (K) was 1.50±0.05 M−1 at an applied voltage of 50 mV.

However, as reported above, the α3β2γ2 receptor binding rate constant (kon) is much slower than in α1β2γ2 channels.

It has also been recently shown that the fusion inhibitor 5-Helix, which binds to the C heptad repeat region of gp41 immediately N-terminal to the MPER, is Kon rate-restricted in it's neutralizing activity, such that Kon is a more dominant factor then equilibrium binding affinity [58].

In these experiments, charged surface residues of CaB, which do not serve as direct ligands of the Ca2+, were neutralized and the overall rate constant for Ca2+ binding (kon = koff * Keq) was shown to reduce significantly in a low ionic strength environment [5].

Here de Koning was on firmer ground.

Koning was married three times.

Koning was born in Amsterdam on July 12 , 1921