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The parasite ligand for P-selectin binding is thought to be PfEMP1, because purified PfEMP1 can bind to P-selectin in vitro (Ref. 89).
PP1 also binds to the kinesin-8 family members Klp5-Klp6 in S. pombe, where PP1 binding is thought to contribute to SAC silencing (Meadows et al. 2011).
Cesium binding is thought to be facilitated by potassium transport system(s) in various microorganisms (Borst-Pauwels 1981; Bossemeyer et al. 1989; Avery 1995).
GAG binding is thought to allow virions to roll on cell surfaces until they encounter a protein ligand [2].
All Wnt-ligands and most of their cognate receptors contain a cysteine-rich domain (CRD), through which their binding is thought to be mediated.
This effect on nucleotide binding is thought to result in increased retention of mutant protein on target membranes leading to the enhanced interaction with a subset of effector proteins [16].
Similar(35)
Subsequently, E2F-6 activity was associated with repression of the BRCA1 promoter using an shRNA approach and its binding was thought to occur in a reciprocal manner with E2F-1 to regulate the promoter [ 24].
Further, alterations in pyrophosphate binding are thought to aid in the modulation of prenyl chain orientation within the active site and most likely modulate the fate of the early intermediates along prescribed mechanistic pathways 30).
Post-translational, dynamic regulation of microtubule-binding is thought to occur by phosphorylation of tau at various serine/threonine residues by various kinases, including GSK3, cdk5, and MARK, among others.
The process for M5SH steps following the strong binding state is thought to be ATP binding dependent, as there were no differences in the stepping kinetics for non-successive strokes, first strokes and successive steps (Fig. 4).
However, finding a targetable protein protein interaction motif with a distinct binding nature is thought to be difficult because binding surfaces are mostly nondescript.
More suggestions(15)
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