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Dr Sattentau believes this binding is the molecular mechanism which triggers peanut allergy.Don't go nutsWhy, even so, most people can eat peanuts without ill effect, is probably a quirk of genetics.
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In addition, GO annotation revealed that binding was the molecular function preferentially assigned to these proteins.
This could be reflected by the trends we observed in the annotations of the genes containing codons under selection: many are involved in defense and protein binding is the most common molecular function.
Among the molecular functions, binding is the most over-represented function, including binding to ATP, protein, nucleotide, DNA, RNA, and several kinds of ions (Additional file 14: Figure S3).
This is because molecular binding is the paramount factor in such ligand cellular system and key structural modifications around ligand binding are expected to create outliers.
II: molecular binding is the paramount factor in such a ligand cellular system, and III, key structural modifications around ligand binding are expected to create singular situations, i.e. cause outliers in a statistical regression.
In the molecular function category, "tetrahydrobiopterin binding" is the first ranking of the prediction (Table 2).
Mannose binding was the only molecular function GO term significantly enriched in genes up-regulated in Mrc1+GFPlo cTMs (Fig. 6B).
Another example of a potassium-binding enzyme is the molecular chaperone Hsp70.
Consistent with their predominant classification in DNA dependent regulation of transcription, DNA binding was the primary shared molecular function among these 64 genes.
Nucleic acid binding was the most enriched molecular function category up-regulated in Li 2 fiber, whereas sugar binding, transferase activity and galactosidase activity were among down-regulated functional categories (Additional file 6C).
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