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This binding is the first step of viral infection.
The statement, which is not legally binding, is the first response by the U.N.'s most powerful body, which has been deeply divided on the Israeli-Palestinian conflict.
In the viral genome and oriP-derived plasmids, ORC binding is the first step in the process of origin licensing [16].
Antigen binding of C1qa binding is the first step in activating the classical complement pathway, whereas CFB and Serping1 are regulators in the alternative and classical complement activation pathways [21].
In the molecular function category, "tetrahydrobiopterin binding" is the first ranking of the prediction (Table 2).
Phosphorylation of BMPR1 by BMPR2 after ligand binding is the first step to trigger the intracellular BMP signaling cascade.
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We verified independently that "binding" is the second most underrepresented GO category after "intracellular" amongst genes in CNV regions.
Interestingly, this binding was the first described direct molecular interaction between intermediate metabolism and the chromatin, whereby a metabolite can impinge on and tweak gene expression [ 14- 16].
In addition, "type I transforming growth factor beta receptor binding" was the first gene ontology category at the molecular function level (Additional file 7: Table S4).
Tamoxifen, which interferes with estrogen for receptor binding, was the first successful targeted therapy and has been the treatment of choice for estrogen receptor (ER -positive brER -positive for more than two decades.
The Phosphoprotein and Glycoprotein are the most repeated terms in R. norvegicus and D. melanogaster, but Acetylation and Nucleotide binding are the third most viewed one in each organism, respectively.
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