Sentence examples for binding is sufficient for from inspiring English sources

While high-affinity ligand binding is sufficient for activation of most canonical signaling pathways, low-affinity binding is required for the activation of the Signal transducers and activators of transcription (Stats) and Phospholipase C-gamma 1 (PLCγ1).

In contrast, lipid II binding is sufficient for antimicrobial activity against vegetative cells.

Both conditions result in the same average distance demonstrating that ATP binding is sufficient for the formation of the NBD sandwich observed in the crystal structure.

Some transporter-like receptors, such as the glucose transporter-like SNF3p and RGT1p from Saccharomyces cerevisiae, appear to be unable to transport, suggesting that binding is sufficient for triggering a conformational rearrangement that is detected by intracellular signaling proteins (Thevelein, 2009).

Some transporter-like receptors, such as the glucose transporter-like SNF3p and RGT1p from S. cerevisiae, appear to be unable to transport, suggesting that binding is sufficient for triggering a conformational rearrangement that is detected by intracellular signaling proteins (Thevelein and Voordeckers, 2009).

Our work with the reconstitution of PERK's paradoxical activation by IPA shows for the first time that no other components of the kinase pathway are necessary and that inhibitor binding is sufficient for activation through the formation of homo-dimers or higher-ordered homo-oligomers.

In this report, we have firstly expressed in stably transfected MDCK II cells a range of truncation mutants lacking up to 78% of the C-terminus of TSP1; these studies indicate that the N-terminal region containing the heparin binding domain is sufficient for basolateral targeting of TSP1.

Since cholesterol was shown to be essential for TcdA- and TcdB- mediated pore formation [24], it might be conceivable that a cholesterol binding region is sufficient for cell attachment allowing subsequent endocytosis.

Under the same premise as above that a single binding site is sufficient for gene regulation, P(Θ→S|S,Θ,φ) can be interpreted as the probability of regulation.

These observations suggest that a single Nup53 membrane binding region is sufficient for NPC assembly at the end of mitosis.

A possible explanation might be that Nup53 can interact directly with membranes and that one of its two membrane binding regions is sufficient for postmitotic NPC formation.