Sentence examples for binding is significantly reduced from inspiring English sources
The EcoNth Thr121 residue influences enzyme binding to DNA, as binding is significantly reduced with the Thr121Ala variant.
Our present data show that E-selectin binding is significantly reduced in c-FOS-overexpressing OvCa cells under flow conditions.
Furthermore, drug enzyme binding is significantly reduced, and quinolones lose much of their ability to inhibit DNA ligation or to form stable ternary enzyme DNA drug complexes.
To test whether the conserved Slou-preferred motif in the lbl FC enhancer mediates the previously described repressive activity of Slou on lbl expression, we mutated this sequence such that Slou binding is significantly reduced, as judged by the PBM E-score of the mutant site (Fig. 3A), and a crucial nearby T-box-binding site is unaffected (Y. Kim, B.W.B. and A.M.M., unpublished).
Although E-selectin binding is significantly reduced in the absence of ESL-1, neutrophil recruitment namely initial rolling, induction of adhesion, and extravasation are unaffected in ESL-deficient neutrophils under diverse inflammatory conditions in vivo indicating a functional compensation by PSGL-1.
The latter was indentified, because these three antibodies did not bind – or their binding was significantly reduced – to an N-terminally truncated PrP variant (ΔF) with a deletion of amino acids 33 134, while it still bound to another variant (ΔE) with a shorter deletion of residues 33 121 (Supplementary Figure S4B).
This binding was significantly reduced in the presence of 5 to 10-fold excess of unlabeled GLV IRES (Fig. 10, lanes 5 6) but unaffected by an excessive amount of yeast RNA (Fig. 10, lanes 7 8).
