Sentence examples for binding is shown to from inspiring English sources
The binding is shown to be negatively cooperative, with the cooperativity resulting from electrostatic interactions between the oppositely charged protein and polymer.
Sialic acid binding is shown to trigger a conformational switch that modulates the affinity for the acceptor substrate and concomitantly creates the conditions for efficient transglycosylation.
This binding is shown to have a variety of effects on numerous signalling pathways, all of which demonstrate some sort of intervention in the progression of OA [ 13, 21, 32, 36, 38, 42, 43, 46, 59, 61, 104, 116].
By measurement of seeded fibril elongation kinetics, both in solution and on a surface using a quartz crystal microbalance, this binding is shown to strongly inhibit further growth of the fibrils.
In this case, the corresponding kinetic paths of binding are shown to be intimately correlated with those of folding and the dynamics becomes quite cooperative.
Interestingly enough, collagen binding was shown to be essential for the virulence of Y. enterocolitica in mice inoculated intragastrically [28].
Because PKC ligand binding was shown to be dependent on phospholipid binding [32], it is perhaps not surprising that our method failed to predict PKC-delta as a druggable site since we do not treat the effects of membrane binding.
However, at the 6 week timepoint DAT binding was shown to be significantly reduced by 48% compared to levels in the EV condition (F2,18 = 5.61, P = 0.013; post-hoc, c.f. EV or GFP, both P<0.05) (Figure 6A).
Furthermore, Gremlin proteoglycan binding was shown to cause tyrosine phosphorylation of ERK1/2 in these systemic endothelial cells.
Similarly, an additional HaloTag-modified assay to measure CREB binding was shown to function equivalently to the commonly utilized high-throughput promoter luciferase reporter assay.
