Sentence examples for binding is required in from inspiring English sources

Genetic studies have demonstrated that the MutL R266), residue implicated in ssDNA binding, is required in MMR [5].

Notice that no hypothesis on the chloroquine:HM binding is required in the reasoning of section 1.1.1 We now discuss the case when the transported form is CQ+, i.e. PfCRT is an active carrier that transports CQ+ in the linear regime (cell C4,1 4 Figure 1).

MLL2 binding is required for changes in chromosome architecture around developmental genes and establishes promoter-enhancer looping interactions in a cell-cycle-dependent manner.

Furthermore, neurabin binds to actin [76] and this binding is required for its localization in dendritic spines [39].

To further investigate whether the C-terminal domain of UNC-116 can bind to MTs and whether this binding is required for its function in establishing dendritic MTs, we first examined the amino acid sequence of the C-terminal region of UNC-116.

It has been shown both theoretically [ 54] and experimentally [ 55] that cooperativity in TF binding is required for this subnetwork to exhibit bistable behavior.

We have shown previously that the normal function of PABPN1 and more specifically its activity in RNA binding is required for OPMD pathology (Chartier et al, 2006).

In addition, RBD mutations have been used to demonstrate that input of RAS binding to the single Drosophila type I PI3K is critical in insulin-pathway-controlled developmental growth (Orme et al., 2006) and that RAS binding is required for PI3K activation by chemoattractants in Dictyostelium (Funamoto et al., 2002).

Our results can be interpreted only using a scheme in which dNTP binding is required for kinetically productive DNA binding.

The presence of functional TBP paralogs in metazoans raises the question why more than one TATA binding factor is required in these organisms while only one such protein is sufficient for proper execution of the transcriptional program in yeast.

These results indicate that the Cap-H2 Mrg-binding motif is required in vivo for condensin II mediated polytene chromosome dispersal, and Cap-H2 molecules with mutations in this motif can suppress gain-of-function phenotypes produced by overexpression of wild-type Cap-H2.