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The N-terminus of GRP94 also contains a peptide binding site [13] and ATP binding is reported to dictate the conformation of the N-terminus and regulate its ability to form quaternary structural interactions [14], [15].
In addition, substrate binding is reported to occur through an induced-fit mechanism.
Second, CTCF binding is reported to mark boundary elements between neighboring genes [ 42].
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The low 11 C radioactivity in the white matter, where GlyT1 binding was reported to be high in in vitro ARG studies, was consistent with our previous ex vivo studies of 125I]IMPB [24] and previous PET studies with other GlyT1 ligands [19 21].
In preweanling animals, across all compounds and treatment protocols, QNB binding was reported to increase in six studies, decrease in two studies, and not change in four studies (Table 5).
A deletion of 2 bp in box B in vivo, which abolishes TFIIIC binding, was reported to result in rearrangement or destabilization of the nucleosomes in the gene-flanking regions [ 39], suggesting these nucleosomes in vivo are organized by TFIIIC-dependent chromatin remodeling.
From these proteins, a special cholesterol binding motif is reported to which the membrane cholesterol binds and modulates their activity.
Also, an on-rate of Ca2+binding for many EF-hand-type Ca2+-binding proteins is reported to be low (Holmes, 2000) and therefore these proteins may be too slow to follow fast [Ca2+]i transients induced by APs.
52, 53 The protein binding of avibactam is reported to be 8%.
Similarly, GTP binding protein EngB is reported to be necessary for normal septation and its disruption leads to extensive filamentation.
Calcium binding protein S100A10 is reported to be overexpressed in renal cell carcinoma (Teratani et al, 2002) and may exert its effect on metastasis formation by stimulating the motility and invasive properties of gastric cancer cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com