Sentence examples for binding is relevant to from inspiring English sources

Whether this binding is relevant to the splicing of fosB pre-RNA within the brain is currently unknown but is a focus of ongoing analysis.

To be certain that this binding is relevant to activation, it should be shown that this variant not only binds but also induces the expected functional result (i.e. activation of TMEM16a currents).

Previous research has investigated the possibility that disrupted EphB2- NMDA R binding is relevant to the development of Alzheimer's disease (AD), a condition that is characterized by severe synaptic impairment.

"What the Spanish government is doing is to take note of a decision of the European Parliament that, even if not binding, is relevant and has strong political value," Luis de Guindos, Spain's economy minister, said at a news conference on the sidelines of the meeting of finance ministers from the Group of 20 nations in Mexico City.

Clearly, only functional binding is relevant for understanding regulation of transcription.

To address the question to which extent the PI binding ability of Pdr16p is relevant to its function in relation to azole resistance, we generated Pdr16pE235A, K267A mutant defective in PI binding.

[Editors' note: the author responses to the second round of peer review follow.] 1) The authors now describe mutations that indicate that the binding mode they see is relevant to catalysis.

Please respond to all of these points by revising the manuscript appropriately. 1) The authors now describe mutations that indicate that the binding mode they see is relevant to catalysis.

However, given that the G U pair is found in a different context in SLVI versus the full-length VS ribozyme, it is not clear if Mg2+ binding at this site is relevant to the activity of the ribozyme.

This substitution is relevant to PI3K binding because an HRAS-D33I mutant showed attenuated binding to p110α and DIRAS1-I37D showed reduced binding to p110β, even though exchange of this residue did not enable RAS binding to p110β or DIRAS binding to p110α, pointing to additional, G2-box-independent determinants of PI3K isoform specificity.

Although the NMR data was collected for the p7 (5a), the high sequence identity between 5a and 1a and the fact that the p7 (5a) residues involved in HMA binding are mostly conserved in p7 (1a) provided us with strong confidence that the HMA binding site reported in this study is relevant to the identified HMA inhibition and likely applicable to other p7 variants.