Sentence examples for binding is not mediated from inspiring English sources

We show that p53 binds BRD4 but that this interaction is not disrupted by JQ1, implying that binding is not mediated by either of the two bromodomains.

We show that Swc2 is required for Swr1 binding to chromatin, and that this binding is not mediated by its interaction with Htz1 because it is not prevented by htz1Δ.

This also suggests that PLSCR1 binding is not mediated by a linear motif contained within the SLPI primary sequence, but is rather related to the recognition of the conformational structure of the WAP domains.

We found that EAEC strain 042 has the ability to bind directly and indirectly to integrin α5 β1; direct binding was not mediated by AAF/II fimbriae and indirect binding was mediated by AAF/II and fibronectin.

Similar results were obtained after expression of the Rup1 Y135F mutant in a ubp2Δ deletion mutant background (data not shown), indicating the residual binding was not mediated by Ubp2.

Furthermore, the interaction between Tim and Plk1 was insensitive to Dnase I treatment, indicating that the binding was not mediated by non-specific DNA or chromatin linkages (Fig. S1).

The equivalent off-rate of Tr1D3 and Tr4 demonstrated that the change in Tr's biotin-binding stability is not mediated through altered subunit interactions.

This would suggest that binding to E931 is not mediated by Mg2+ as was observed for the other two residues.

Fis1 cannot bind GABARAPL1, confirming that the binding between TBC1D15 and GABARAPL1 is not mediated indirectly through Fis1.

The RNase II degradosome association is not mediated by binding of the proteins to a common RNA substrate as shown by its insensitivity to RNase pretreatment.

The association of RNase II with RNaseE is not mediated by binding of the proteins to RNA substrates as shown by its insensitivity to RNase treatment.