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As a result of this longer active site loop, HCA binding is not influenced by a substrate being present.
Thus, we take the assumption that the Grb2-SOS binding is not influenced by Grb2 association to phosphorylated EGF receptor or phosphorylated Shc.
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HAMLET binding was not influenced by membrane fluidity, charge or 18∶1 fatty acid acyl chain composition.
KDED2 binding was not influenced by any of the aptamers tested against it.
Nevertheless, SP1 binding was not influenced by estradiol, pointing to independent mechanisms of recruitment.
LPS binding was not influenced by anticoagulants, while internalization seems to occur at earlier stages with EDTA.
Interestingly, the strength of binding was not influenced by valency, even when the average valency was increased from 1.2 to 8.3, a reduction of the monovalent population from around 180 particles of 500 (36%) to less than 1 in 500 (0.2%).
The results showed that the protein binding ability is not influenced when they are administrated simultaneously.
Most of these residues also undergo rotamer averaging in the hinge-closed complexes (hE:FOL NADP+, hE THF NADP+, and hE THF), showing that the flexibility is an intrinsic property of the adenosine-binding subdomain and is not influenced by the nature of the bound ligands.
unidirectionally interacting processes The binding of one ligand, e.g. ligand L, is not influenced by binding of the other one.
But unexpectedly the Egr-1 binding activity to the cyclin D1 promoter is not influenced by SP1 binding (Yan et al. 1997).
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