Exact(3)
If this is also the case in patients with CD, this would explain the reduced level of serotonin metabolites that was found in cerebrospinal fluid of dystonia patients, and supports also our postulate that the currently observed lower SERT binding is not caused by an increased release of serotonin [11].
We intended to take into account only cations interacting exclusively with RNA atoms, whose binding is not caused by other molecules.
The simulation results indicate that the phosphorylation of Ser did not affect the local conformation nor the overall stability of the PTB domain, suggesting that the loss of APP binding is not caused by major conformational change in the phosphorylated FE65 PTB2 structure.
Similar(54)
The differences in S1-induced TM binding were not caused by altered S1 binding, because actin C-terminal modification did not affect S1 binding to actin (Fig. 4D, inset).
The Htt lowering is not caused by antibody binding artifacts or Htt cleavage, as multiple antibodies detect comparable reduction and there is no obvious increase of possible Htt fragments of lower molecular weights that may account for the lowering of the full length protein.
Moreover, the brief detachment of the leading head observed as a foot stomp in the presence of ATP is not caused by ATP binding to the head because the sharply kinked conformation was never observed before the brief detachment of the leading head.
Thus the failure of these mutants to oligomerise is not caused by reduced nucleotide binding.
To verify that this differential enrichment in RNA Pol II and H3K27me3 binding sites was not caused by a bias in read mapping due to differences in DNA copy number, we genotyped the cell lines using the Illumina Human Hap 1M chip.
These experiments strongly suggest that the effects of DHA treatment described above were not caused by binding to an ionic receptor or by modifying membrane properties.
These results also suggest that the observed differences between the groups were not caused by different binding capacities to the GAD65Ab epitope defined by b96.11.
This suggests that the binding is not primarily caused by binding to TRAILR2 but rather reflects binding to endogenous TRAILR4 and/or heterocomplexes of TRAILR2 and TRAILR4.
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