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In particular, more detailed biophysical analysis of the behavior of active caspase-8 and of Bid-FL binding is needed to understand the interactions between the various components of the platform.
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Here, it is demonstrated that more data on TTR-binding compounds is needed to cover the potential binding potency of compounds without these typical characteristics.
The figures are significant because they undermine the EU's insistence that a new legally binding agreement is needed to get developing countries to cut emissions further.
C1q may suppress the synergistic effect of p53 and WOX1 in inducing apoptosis [26], [27], suggesting that a balanced p53/WOX1 binding interaction is needed to control cell survival and death in response to C1q.
The increase in binding protein is needed to protect RuBisCO from degradation or allow the assembly of more RuBisCO holoenzymes, suggesting the maintenance of Calvin cycle under low temperature.
Further investigation of FCoR-binding proteins is needed to identify such partners.
Ms. Bear and other environmental leaders believe that some sort of binding preservation plan is needed to ensure that officials in the future do not abandon the valley to developers.
They immediately began to read the names of the more than 11 million people who signed a petition demanding the same fair, ambitious, and legally binding agreement that is needed to avoid dangerous climate change and usher in a global clean energy economy.
In both cases receptor binding and consequent release of the C-tail was shown to facilitate dephosphorylation of non-visual arrestins, which enhances clathrin binding just when it is needed to recruit the arrestin-receptor complexes to the coated pit (Lin et al., 1997, 2002; Kim et al., 2002).
Further study of these PG-expressed OBPs, especially their binding to sex pheromone components is needed to confirm its function.
The lack of an adequate protein entropy term can result in an overestimation of binding free energy, and more work is needed to examine the effect of this on such calculations.
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