Sentence examples for binding is localized to from inspiring English sources
Together, these data indicate that while multiple domains of Smad3 are capable of interacting with Sox17, the strongest binding is localized to the linker and MH2 regions from amino acids 146 425.
In parallel with our in vitro studies, a punctate distribution of FXa was observed, in accord with the notion that FXa binding is localized to the platelet surface during thrombus formation.
The results demonstrate that ssDNA binding is localized to the C-terminal region that contains the OB-fold domain, while a tandem helix-hairpin-helix (HhH 2 motif contributes significantly to dsDNA binding.
In other figures, it was critical for us to be able to test just the motor domain to show that Rab6 regulation of KIF1C's MT binding is localized to the motor domain alone.
Specific ANF binding was highest in the glomeruli, but lower levels of specific binding were localized to the inner medulla and the interlobular arteries.
Given, for example, that the Cav3-binding site is localized to the lid region makes it likely that ligand binding will have an immediate impact on the Cav3 Popdc1 interaction.
This finding is compatible with previous observations that the PA-binding site is localized to the extreme N-terminus of PB1 [28], [28].
These data suggested that the Fn-binding activity is localized to a predicted β-strand or the flanking disordered regions (L148 I152 and P158 V164).
There are some examples of PfEMP1 variants where binding to host receptors is localized to a single domain (for example, CIDRα binding CD36 [49] or DBLβC2 binding ICAM-1 [50].
Full-length HcpA (residues 18 to 175) as well as the truncated versions bound PLG (Fig. 3B), thus indicating that the binding site for PLG is localized to the central domain of HcpA.
