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Inhibition of DNA binding is interpreted to indicate that the A-ZIP is forming a heterodimer with the B-ZIP domain and thus prevents the B-ZIP from binding to DNA.
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The positive value for ω is interpreted to indicate that binding of IHF to a duplex increases the probability of a second IHF dimer binding next to it by 37-fold, consistent with the greater than unity values for the Hill coefficient observed above.
The effect term "activation; binding" is interpreted as that the binding activity of tp:produces is enhanced by tp:reactants.
Also in many (but not all) SPET and PET studies, reduced SERT binding has been interpreted to indicate reduced 5-HT function.
Our observations are reminiscent of the studies of transcription factor binding in the Drosophila blastoderm where disparate transcription factors show similar binding profiles and this has been interpreted to represent a strong influence of chromatin accessibility on transcription factor binding [72], [73].
It has previously been shown that the T>C variant in the ICR region affects OCT4/SOX2 binding, and our data can be interpreted to imply that the variant interferes with gonadal switching from paternal to maternal imprinting.
These findings may be interpreted to indicate that CO binding to cytochrome aa3 at low CO/O2 in vivo increases extramitochondrial pH relative to that within the mitochondrial matrix.
Differences were, however, observed in their concentrations in blood and several organs in vivo, which were interpreted to be primarily related to ZEGFR:2377 binding to peripheral EGFR.
This result was interpreted to mean that the U1-C was a sequence specific RNA-binding protein.
The binding cooperativity, or heterotropic linkage, is interpreted with respect to linked conformational equilibria of both SNF and its RNA ligand and so represents an example of protein RNA allostery.
Genetic regulatory information encoded in DNA binding sites, such as enhancers and promoters, is interpreted by a network of transcription factors (TFs) [ 3].
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