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The team's previous research has indicated that opioid receptor binding is increased in people who are dependent on alcohol, when compared to social drinkers, but "what we don't know is whether these differences were there before alcohol dependence or were a result of heavy long-term drinking," Weerts said.
Consistent with this notion, previous reports have shown that FOXP3 DNA binding is increased, in a cyclosporine A-sensitive manner, upon stimulation of T cells through the T cell antigen receptor [25], [30], [40].
M1 and M2 receptor binding is increased in the striatum of female rats following repeated cocaine injections [ 405].
36 TSPO binding is increased in activated microglia 38 and can be visualized with TSPO-binding SPECT radioligands.
This binding is increased in the presence of heme [ 48], consistent with the reported dependence between artemisinin activity and hemoglobin digestion [ 56].
Plx1 binds to chromatin interacting with the Mcm complex through its polo box domain and its binding is increased in the presence of stalled replication forks.
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In the present study, M1- and M2-like muscarinic receptors binding was increased in the striatal and hippocampal regions of post-pubertal NVH lesioned rats.
Of 420 kinase proteins screened, KBU2046 had highly selective effects, significantly changing the binding of only 17 (4%): binding was increased in 10 and decreased in 7 (Fig. 6a and Supplementary Fig. 17a).
Hyaluronan binding was increased in cells transfected with either CD44S or CD44E.
Oxygen-mediated complex formation was implicated because binding was increased in oxygenated buffer, reduced in nitrogen-purged buffer, and prevented by reduction with dithiothreitol or 2-mercaptoethanol.
Consistent with this negative correlation, ABA binding was increased in Daudi cells treated with sialidase (Figure 6B), similar to the enhanced binding of PNA observed upon sialidase treatment.
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