Sentence examples for binding is important for from inspiring English sources
Paz et al. have recently shown that the TRAF6-binding site (455-PEENEY-460) of MAVS also binds to TRAF3 and that this binding is important for MAVS signaling (Paz et al., 2011).
Having shown that the extended dsRBD of Dcr1 binds dsRNA with high affinity, we set out to test if RNA binding is important for import/export-promoting activity of the dsRBD of Dcr1.
Understanding the mechanism of the reduction in enzymatic activity due to a point mutation in PAH and its restoration by PhC binding is important for the design of more effective PhC drugs.
Taken together, these findings suggest that GAG binding rather than CXCR3 binding is important for CXCL10's anti-proliferative effect.
Nucleotide binding is important for association of EHD2 with the plasma membrane, since a nucleotide free mutant (EHD2 T72A) failed to do so in cells [23].
This shows that Ca2+ binding is important for Azot function.
These results demonstrate that residues seemingly only involved in general DNA binding are important for catalytic activity and imply that base excision is driven by binding energy provided by the entire substrate interface of this novel DNA binding architecture.
Thus, the sites defined by protein binding are important for the functional activity of immunoglobulin enhancers, with the sites that bind proteins restricted in their cellular distribution playing the most important roles.
Categories 52 (protein kinase activity) and 27 (heparin binding) are important for characterizing both the transition from hMSC to hOST and the differences between the two intermediate states.
Again the AD169 data really argues against KAP1 binding being important for controlling latency since KAP1 is recruited to this genome perfectly well but does not provide the same level of control as it apparently does in TB40-E.
