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Tight binding is facilitated by 10 hydrogen bonds and a number of hydrophobic interactions.
The ubiquitin ligase Arkadia controls the degradation of Smad7 itself and its binding is facilitated by axin, a scaffold protein that plays a crucial role in Wnt signaling.
Computational and experimental evidence from HuR RNA-IP in human B cells and cells transfected with ADAR siRNAs showed that HuR binding is facilitated by ADAR binding to RNAs.
In addition, any string which contains only one mismatch is also considered a hit, but is given a count of 0.1 rather than 1. 3. Melting Temperature Profile (MT) – It is possible that TF binding is facilitated by conformational adjustments in promoter DNA, which depends on the stability of the helix.
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Previous studies have identified that recombinant eEF1α binds to the 3′UTR of ß-actin mRNA [18] and that binding was facilitated by domains I and III.
c-ETS2 binding was facilitated by an active chromatin distinguished by acetylated histone H3 orchestrated by histone acetyl transferase GCN5 and followed by HBO1 mediated histone H4 acetylation.
The prediction of small molecule binding sites is facilitated by their tendency to bind in pockets on the surface of the protein, due to the requirement of forming sufficient energetically favorable contacts.
The comparative visual inspection of the different binding patterns is facilitated by a depiction mode, which takes the constant part into account.
However, these flavors must have some similarities: the binding of ERK1/2 is facilitated by both 3A and Δ7 mutations in arrestin-2 and -3 (Coffa et al., 2011a).
However, the same report also suggests that histone H1 binding to DNA is facilitated by CDK1 activity, suggesting that the regulation of subcellular localization is responsible for appropriate histone H1 activity only during M-phase.
At least partially, binding to the cells is facilitated by different receptor proteins.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com