Sentence examples for binding is enriched at from inspiring English sources

This binding is enriched at the transcriptional start sites (TSSs), compared to the ends of transcripts (TxEnd), other gene body, or intergenic regions.

Esa1 binding is enriched at the rDNA, and histone acetylation at the rDNA is reduced in the esa1 mutant (Clarke et al. 2006).

Hmt1 binding is enriched at many of these tDNA alleles and mutants lacking Hmt1 or its catalytic activity display higher levels of the corresponding tRNA abundance.

Herein, using chromatin immunoprecipitation experiments followed by massively parallel sequencing analysis (ChIP-seq) we find that in PC3 prostate cancer cells ALKBH3 binding is enriched at transcription associated genomic loci, where ssDNA is accessible.

As expected, AR binding was enriched at the enhancer-associated accessible regions, while CTCF occupied both enhancers and promoters (Taslim et al, 2012).

However, full-length Scm3 (containing the Ndc10 and DNA binding domains) is enriched at centromeres through all of the cell cycle stages (Xiao et al., 2011), consistent with live cell imaging, and genetic studies suggesting the importance of Scm3 after Cse4 deposition (Camahort et al., 2007).

Cohesin binding to chromosomes in vivo is enriched at centromeres and at cohesion-associated regions (CARs) along the chromosome arms (Laloraya et al., 2000; Onn et al., 2008), and is highly salt resistant (Ciosk et al., 2000).

For example, KDM5C/JARID1C/SMCX interacts biochemically with c-MYC in mouse ES cells and KDM5C is enriched at c-MYC binding sites [ 71].

In this paper, we demonstrate that indeed our method allows for the detection of a peculiar type of sequences, hitherto uncharacterized, which is enriched at the DCC binding regions.

Intriguingly, while Set1 is enriched at highly expressed and repressed loci, Set1 binding levels do not generally correlate with the levels of transcription.

Within the category molecular function, binding-related sub-categories such as cation binding, ion binding, and nucleoside binding were enriched.