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Finally, we demonstrate that fluorescein-ghrelin(1 18) binds specifically to heart tissue in situ, and its binding is displaced by both wt ghrelin and hexarelin.
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Actually, the contralateral binding was displaced by cold VUIIS1008 and DPA-714 supporting the view that the modest and transient increase of [18F] VUIIS1008 binding is TSPO specific (Figs. 5 and 6).
Basal and induced binding was displaced by adding 50-fold excess cold ATF/CRE and NF-κB oligonucleotide (competition).
I S100A8/A9 binding was displaced by 50-fold molar excess of cold ligand or 10-fold molar excess of anti-S100A8.
Ser and Ser are located in a large AI (autoinhibitory) insertion in the FMN-binding domain, which is displaced by CaM binding during activation [ 23].
The binding sites for Hakai and p120 are closely apposed in the intracellular juxtamembrane domain of E-cadherin and, accordingly, p120 is displaced by the binding of Hakai to E-cadherin before endocytosis [ 9].
It is possible that HEXIM is displaced by the binding of hnRNP proteins that occurs upon P-TEFb release [51], [52], [54].
Simulations revealed that an organized water is displaced by zanamivir in binding to NEU2 and NEU3 and confirmed the critical importance of engaging the binding pocket of the C7 C9 glycerol sidechain.
Specific [H]-E2 binding was displaced in the following ranking order by E2 >> Tam > BPA, while T possessed only weak displacement activity.
At a minority of sites, a peak of H3K4methyls signal occupies the site of future GR binding, suggesting a well-positioned nucleosome that is displaced by GR.
Copper is displaced by fibre optics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com