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PHD2 enzyme deactivation due to PHI-1 binding is described by an inhibitory direct effect model.
Protein binding is described by the equation fm = (Km × [L])/{1 + (Km × [L])} where fm = fraction bound-protein, Km = equilibrium constant derived from Gm = binding free-energy, and L = lipid.
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In the final example covered in this section, protein stabilization by antibody binding was described by Tiyanont et al. who monitored protein dynamics during activating- or inactivating-antibody binding to the regulatory region of human Notch3.
In that work, the authors designed a synthetic, bistable gene circuit based on the predictions of a simple mathematical model consisting of two ordinary differential equations where the repressor binding was described by Hill functions.
An increase in C- R -PK11195 binding was desC- R -PK11195nin and C- R -PK11195 the temporoparietal, cingulated and entorhinal cortices of AD patients as a sign for strong microglia activation compared with controls [ 60].
A binding site is described by any amino acid for which at least one heavy atom is closer than 4.5 Å from any heavy atom of the bound pharmacological ligand.
The conventional binding experiment is described by the equilibrium between protein-bound 14-SASL and 14-SASL in the aqueous medium 18where FAw is free fatty acid in water.
The state "on" of TRAP, which is defined as the conditions that enable the binding on mRNA, is described by TRAP on = TRAP AND TRP AND NOT RtpA).
The binding of Pal L1 to the H5-modified sensor surface is described by a typical binding curve (orange curve).
A formalism based on the Green's function technique is used for the calculations while the model is described by tight-binding Hamiltonian.
In the limit of an in finitely large binding a finity where the PFK activation is described by a Hill function, as in Sel'kov model [ 12], the capability to generate inward propagating waves is lost.
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