Sentence examples for binding is critical for from inspiring English sources

Although FcγR binding is critical for IgG's effector functions such as antibody dependent cell-mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC), FcγR does not appear to significantly affect IgG's PK properties.

Such binding is critical for dot lattices to appear as having an orientation.

Taken together, these results show that PRC binding is critical for chromatin looping at the INK4b-ARF-INK4a locus.

Cohesin binding is critical for long-range chromatin interactions between the enhancer and the promoter and is important for β-globin gene expression in human cells.

DOI: http://dx.doi.org/10.7554/eLife.00666.013 10.7554/eLiFigure66.014 Figure 7 figure supplement 2. Rho1 binding is critical for Dia localization in embryonic tubular organs.

These results indicate that a GXXXG motif of C99, predicted from structural analysis to be essential to cholesterol binding, is critical for SREBP1-mediated regulation of HMGCR expression.

Residues in the PHO1 SPX domain involved in PP-InsPs binding are critical for its Pi export activity, and the interaction between SPX proteins and the PHR1 transcription factor, which results in PHR1 inactivation, is promoted by PP-InsPs.

The Iso323-Leu324 residues of the CXCR2 CTD required for the CXCR2/LASP-1 binding are critical for binding of adaptor protein-2 (AP-2) and Hsp70 interacting protein (HIP) and CXCR2 mediated chemotaxis [18], [19], [30].

Previous research has suggested that the levels of tubulin mRNA transiently increase during apoptosis and that events occurring downstream from tubulin binding are critical for the generation of apoptosis [ 38].

Importantly, we discovered that valine 337 in the site 2 binding loop is critical for signaling without contributing to binding.

We replaced endogenous WDR5 in mouse ESCs with a RNA binding mutant, WDR5 F266andand found that the RNA binding interface is critical for the accumulation of nuclear and chromatin WDR5.