Sentence examples for binding is central to from inspiring English sources

Effector binding is central to a number of essential activation processes and provides essential information on interactions involved therein.

While talin binding is central to integrin activation, other integrin-binding proteins have also been implicated.

(Transport to what and for what purpose, and is it consistent with the cellular concentrations?) Ligand binding is central to the function of hemoglobins.

Upon induction of autophagy, Beclin-1 interacts with class III PI3-kinase/Vps34, and this binding is central to the recruitment of autophagic proteins to the pre-autophagosomal structure for nucleation.

Coupled folding-binding is central to the function of many intrinsically disordered proteins, yet not fully understood.

There are data that suggest that since C4 must be activated and must bind to a target before C3, it is the blocking of C4 binding that is central to classical pathway inhibition [55].

Our findings indicate that the site 2 binding mode is central to signallosome formation for Norrin mediated signalling.

We show that polypyrimidine tract-binding protein (PTB) is central to one such complex that forms in apoptotic cells.

The microtubule-binding protein tau is central to the regulation of axonal outgrowth and cellular morphology, as well as neuronal transport (1– 3).

The nucleosome remodeling activity of Chd1l is dependent on PAR synthesis, indicating that the PAR-binding macro domain is central to its function as a chromatin remodeler (Ahel et al., 2009; Gottschalk et al., 2009).

The nucleotide-binding domain (NBD/NACHT) is central to all NLRs and is believed to oligomerize in an ATP-dependent fashion in response to specific stimuli, thus leading to NLR activation.