Sentence examples for binding is believed to from inspiring English sources

To signal, FGF19 and FGF21 require co-receptor βKlotho (KLB) to act in concert with FGF receptors, and yet there is appreciable variance in the C-terminal sequences of these two novel metabolic hormones where binding is believed to be primary.

Although its ablation did not affect signaling, TAB1 binding is believed to regulate the TAK1 catalytic activity.

In the induced-fit model, substrate binding is believed to induce conformational alterations in the active site to cause a new conformation for the entire enzyme.

MVI binding partners interact with one out of two partner recognition sites (one charged and one hydrophobic) and this binding is believed to be important for cargo transport or its anchoring to the actin cytoskeleton (see [ 4]).

However, it is well-known that high ionic strength media (such as ∼0.1 M NaCl) suppress nonspecific binding due to compression of the electrostatic double layer, therefore binding is believed to be the result of specific antibody antigen interactions.

As substrate binding is believed to be coupled to protein conformational changes relevant to the transport cycle, describing the binding mode of the substrate in a detailed manner is one of the first steps in a mechanistic characterization of GlpT.

This was similar to some other invertebrates C-type lectins [51], [52], and such binding was believed to be necessary for the opsonization C-type lectin mediated in invertebrates against invaders [53].

Firstly, hydrogen atoms on the benzene ring were substituted with acetamido groups to reduce protein binding (protein binding was believed to cause anaphylactoid reactions) giving rise to the acetrizoates and diatrizoates.

Attenuated metal-binding is believed to improve the selectivity and safety profile of CYP inhibitors, compared to azole antifungal drugs, by increasing contributions of specific drug protein interactions in binding affinity at the expense of nonspecific drug metal interactions via less avid metal-binding groups.

Attenuated metal-binding is believed to improve the selectivity and safety profile of the fenarimol analogues, compared to the azole antifungal inhibitors, by increasing the contributions to binding affinity by specific drug protein interactions at the expense of nonspecific drug metal interactions.

The C-spine is completed upon ATP binding and is believed to play a role in ATP binding and catalysis (Fig. 4C).