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Specific [3H]pirenzepine and [3H]AFDX-384 [3H]AFDX-384lso seen in the dorsal hippocampus (Figure 3a, binding

The tightness of binding is also seen in gel-shift assays, where both D1 and D2 give clear shifts that are saturable.

Similarly, IIH6C4 and VIA4-1 immunoreandivity and laminin binding were also seen in total lysates of DG-deficient cells after overexpression of LARGE (DGKO + Ad-LARGE).

Each conjugate bound HER2 with affinity similar to that of trastuzumab, and comparable binding was also seen by ELISA (SI Figure S3).

The additive effect of TNFα and hypoxia on HIF-1 binding was also seen at the HIF-1α protein level, demonstrating that HIF-1 serves as a convergence point for hypoxia and inflammatory signalling pathways in RA FLS.

A positive correlation between Ubx and Hth binding profiles is also seen in each tissue (Supplementary Figures S3C and S3D).

We next asked whether the observed Pellino2 peptide binding preference is also seen for the other Pellinos.

Having one target-binding site is also seen in the H/ACA box snoRNAs found in Trypanosomes [ 39].

Preferential binding of Tel1p to short telomeres is also seen when short telomeres are generated by deleting YKu or by deleting a telomerase subunit (Hector et al. 2007).

This under-representation is also seen with DNA-binding TAPs (D-TAPs) having homologues in metazoan genomes, as none are seen in areas of high or very high recombination (R ≥ 3).

In addition, higher molecular weight bands which might represent complexes formed between FLAG-optineurin and other optineurin binding partners were also seen.