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To observe whether E2 binding is able to enhance Raji cells' proliferation, we detected the proliferation of Raji cells after E2 stimulation.
Since the Synapsin I ATP binding pocket is localized in the synapsin domain primarily involved in actin binding [69], [72], we investigated whether staurosporine binding is able to affect the synapsin I-actin interaction.
Surface plasmon resonance (SPR) detection of protein binding is able to determine the kinetic and thermodynamic parameters of protein complexes by direct monitoring of the binding event in real time.
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Peptides designed to interfere with p53/p73 binding were able to sensitize breast cancer cells to chemotherapeutic drugs (143).
MiD51 mutants deficient in ADP binding are able to recruit Drp1 to mitochondria [ 38, 41] and support mitochondrial division under normal conditions [ 41].
Particularly, a peptide that specifically blocked HA-RHAMM binding but not HA-CD44 or HA-TLR binding was able to block fibroblast migration and alter wound repair in wild-type but not RHAMM-knockout mice.
Therefore, CaM activates CaM KI by displacement of its binding domain, and the capability of CaM to bind with CaM KI binding domain is able to indicate the activity of CaM to interact with CaM KI.
Four SAA3 molecules bind together in solution to form a hydrophobic central channel that, according to predictive binding studies, is able to bind retinol.
Competing with RANK for RANKL binding, OPG is able to prevent osteoclastogenesis activity [ 8, 11].
We show that the resulting corrected binding signal is able to rank peaks better than peak-callers such as MACS.
Apparently, the binding energy is able to provide some but not all of the energy required to compensate for the destabilizing effect of the mutation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com