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Allosteric regulation of ligand binding is a well-established mechanism regulating the function of G protein-coupled receptors (GPCR).
It is interesting to note that elevated MEK/ERK signalling stimulates AP-1 complex formation which is a well established binding-partner of NFAT that supports NFAT-mediated gene transcription (Macian et al, 2000, 2001).
SELEX is a well established in vitro selection tool to analyze the structure of ligand-binding nucleic acid sequences called aptamers.
A trained architect, Hardwicke is a well established production designer.
It is a well established, but not incident-free, science.
Alcohol is a well established breast cancer risk factor [19].
The PSS is a well established measure.
Ocular damage from radiation treatment is a well established phenomenon.
DFO is a well established hypoxymimetic agent [ 26].
Lactotrophs are a well established estrogen-responsive cell.
Loss of 14-3-3 14-3-3 14-3-3ll estabinding, but the consequences of dephosphorylatisn are only nowelling uncovestablished
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