We examined membrane expression of C2-O-sLeX, selectin binding, invasion of human colon and hepatic carcinoma cell lines, and mRNA levels of alpha-2,3 fucosyltransferase (FucT-III) and core 2 beta-1,6 N-acetylglucosaminyltransferase (C2GnT1) genes, necessary for C2-O-sLeX synthesis, by quantitative reverse-transcriptase (RT) PCR.
Likewise, C. jejuni OMC contains lipid-containing components such as lipoglycans, which play important roles in binding, adhesion, and invasion of human epithelial cells in vitro.
Most Opa proteins mediate invasion of human cells via binding to human carcinoemybryonic cellular adhesion molecules (CEACAMs) [13].
Y. Zou et al. present data showing that Decorin, a decidua-derived TGF-binding proteoglycan, inhibits the proliferation, migration, and invasion of human trophoblast cells.
Similarly, the binding of S100A8/A9 to RAGE was shown to promote migration and invasion of human breast cancer cells through actin polymerization and epithelial mesenchymal transition [ 114].
Tenenbaum, T., Bloier, C., Adam, R., Reinscheid, D. J. & Schroten, H. Adherence to and invasion of human brain microvascular endothelial cells are promoted by fibrinogen-binding protein FbsA of Streptococcus agalactiae.
Tenenbaum, T. et al. Streptococcus agalactiae invasion of human brain microvascular endothelial cells is promoted by the laminin-binding protein Lmb.
A microfluidics assay to study invasion of human placental trophoblast cells.J R Soc Interface.
Xu, L. et al. MEK4 function, genistein treatment, and invasion of human prostate cancer cells.
These liposomes, at nanomolar concentrations of protein, inhibited invasion of human erythrocytes in vitro by the malaria parasite Plasmodium falciparum.
